Where is jab tech located
While there are already existing Ebola vaccines, Oxford scientists hope the new jab — which targets both the Zaire and Sudan species — will have a wider reach. The university is now recruiting volunteers for Phase 1 trials, with the first vaccinations set to take place on Thursday.
In the new study, 26 participants aged 18 to 55 will receive one dose of the vaccine. They will be monitored over a six-month period, with results expected in the second quarter of Known as viral vectors, such technology has been researched for decades, with two new vaccines using adenoviruses developed and used during the Ebola outbreaks in West Africa and the DRC.
Instead of carrying these virus proteins into the body, lab-generated mRNA tells human cells to create them, so that the immune system can recognise and fight a future infection. On that basis, the effectiveness of the vaccines could be increased to as much as 95 per cent, the researcher said.
Norbert Pardi, a vaccine specialist at the University of Pennsylvania, has used mRNA to formulate several antigens in a single vaccine. Antigens cause immune systems to produce antibodies, and Pardi hopes his approach, already tested on mice, will "induce protection from multiple, diverse flu strains". However the technology does pose additional problems, such as the need to be stored at very low temperatures, unlike current flu vaccines that can be kept in regular refrigerators.
For drugmakers, the prospect of producing an mRNA vaccine to ward off the flu is an appealing one, said Jamila El Bougrini, a biotech specialist at stock market analyst Invest Securities. In Pics Interesting facts about billionaire Jack Ma. When wild jumbos disrupt life in 'Kashmir of the South'. People use mental shortcuts to make difficult decisions.
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